Köpfe

Werner Dammermann

Dr. rer. nat. Dammermann
Titel: Dr. rer. nat.
Aktuelle Position: ZTM-BB / Laborleiter
Fachbereich: Biochemie
Einrichtung: ZTM-BB
Dienstadresse:

Medizinische Hochschule Brandenburg Theodor Fontane
ZTM-BB - Zentrum für Translationale Medizin Brandenburg
Hochstraße 29
14770 Brandenburg an der Havel
Haus 11 /2. OG / Raum 3.03

Diensttelefon: 03381-411671
Dienst-E-Mail: Werner.Dammermann@mhb-fontane.de
 
In der MHB seit: 01.03.2016
Forschung: Immunologie, Gastroenterologie, Hepatologie, In-Vitro-Diagnostika
Lehrschwerpunkt(e): Immunologie, Biochemie, Molekularbiologie

Heureka!

Curriculum Vitae
Personal data: Born on June 20th, 1979, in Hamburg, Germany
 
Nationality: German
 
Education and Degrees
Gelehrtenschule des Johanneums, Hamburg, Abitur: 1998
University Hamburg, Biochemistry, Diplom: 2004
University Hamburg, PhD: 2007
 
Professional Carreer
  • Project leader “Cellbased immunoassays”, Euroimmun AG, Lübeck, Germany (2007-2010)
  • Postdoc Senior and Laboratory Head in the group of Prof. Dr. Stefan Lüth, 1. Department of Medicine, University Medical Center Hamburg-Eppendorf (2011-2015)
  • Project leader in the group of Prof. Dr. Udo Schumacher, Department of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf (2016-present)
  • Laboratory Head of the Center for Internal Medicine II (Prof. Lüth), University Hospital Brandenburg, Brandenburg Medical School (2016-present)
  • Laboratory Head of the Center for Clinical and Translational Research Brandenburg (ZKTG-BB), Brandenburg Medical School (2018-present)
Present Status
  • Postdoc Senior at Department of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, (since 2016)
  • Laboratory Head of the Center for Internal Medicine II (Prof. Lüth), University Hospital Brandenburg, Brandenburg Medical School (since 2016)
Research Interests
Immunology/cellular immunity, In Vitro Diagnostics, Gastroenterology, Hepatology
 
Teaching Experience
Biochemistry, Molecular Biology, Cell Biology, Immunology
 
Fellowships and Awards
Award of the Deutsche Leberstiftung 2014

Funding of Current Research Projects
1 Brandenburg Medical School, 2 EU, 1 DFG, various industrial fundings
 
Number of Publications in Refereed Journals
22 peer-reviewed journal papers
 
Number of Contributions to Meetings and Conferences
>70 contributions to meetings and conferences
 
Number of Patents
1
Publikationen
Selected publications:
 
1. Bröker K, Sinelnikov E, Gustavus D, Schumacher U, Pörtner R, Hoffmeister H, Lüth S, Dammerpmann W. Mass Production of Highly Active NK Cells for Cancer Immunotherapy in a GMP Conform Perfusion Bioreactor. Front Bioeng Biotechnol. 2019 Aug 13;7:194. doi: 10.3389/fbioe.2019.00194. eCollection 2019.
 
2. Bröker K, Terzenbach R, Bentzien F, Lüth S, Dammermann W. Complement factors C3a and C5a mimick a proinflammatory microenvironment and increase HBV IGRA sensitivity. J Transl Med. 2019 Jan 3;17(1):6. doi: 10.1186/s12967-018-1752-8.
 
3. Zhang B, Watt JM, Cordiglieri C, Dammermann W, Mahon MF, Flügel A, Guse AH, Potter BVL. Small Molecule Antagonists of NAADP-Induced Ca2+ Release in T-Lymphocytes Suggest Potential Therapeutic Agents for Autoimmune Disease. Sci Rep. 2018 Nov 13;8(1):16775. doi: 10.1038/s41598-018-34917-3.
 
4. Dammermann W, Mihajlov V, Middendorf B, Mellmann A, Karch H, Ullrich S, Lüth S. Anti-Shigatoxin 2 antibodies in EHEC O104:H4 infected patients may predict hemolytic uremic syndrome. J Gastroenterol Hepatol. 2018 Jul;33(7):1353-1356. doi: 10.1111/jgh.14082. Epub
2018 Mar 12.
 
5. Karimova M, Beschorner N, Dammermann W, Chemnitz J, Indenbirken D, Bockmann JH, Grundhoff A, Lüth S, Buchholz F, Schulze zur Wiesch J, Hauber J. CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X. Sci Rep. 2015 Sep 3;5:13734. doi: 10.1038/srep13734.
 
6. Dammermann W, Bentzien F, Stiel E-M, Kühne C, Ullrich S, Schulze zur Wiesch J und Lüth S. Development of a novel IGRA assay to test T cell responsiveness to HBV antigens in whole blood of chronic Hepatitis B patients. J Transl Med. 2015 May 13;13:157. doi: 10.1186/s12967-015-0513-1.
 
7. Dammermann W, Wollenberg L, Bentzien F, Lohse A, Luth S. Toll like receptor 2 agonists lipoteichoic acid and peptidoglycan are able to enhance antigen specific IFNgamma release in whole blood during recall antigen responses. J Immunol Methods 2013 Oct 31;396(1-2):107-15.
 
8. Cordiglieri C, Odoardi F, Zhang B, Nebel M, Kawakami N, Klinkert WE, Lodygin D, Lühder F, Breunig E, Schild D, Ulaganathan VK, Dornmair K, Dammermann W, Potter BV, Guse AH, Flügel A. Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system. Brain 2010 Jul;133(Pt 7):1930-43.
 
9. Dammermann W, Zhang B, Nebel M, Cordiglieri C, Odoardi F, Kirchberger T, et al. NAADPmediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist. Proc Natl Acad Sci U S A 2009 Jun 30;106(26):10678-83.
10. Dammermann W, Guse AH. Functional ryanodine receptor expression is required for NAADPmediated local Ca2+ signaling in T-lymphocytes. J Biol Chem 2005 Jun 3;280(22):21394-9.