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Racha El Hage
Titel: | Dr |
Aktuelle Position: | Projektleiterin Labor (Postdoc) |
Fachbereich: | Gefäßchirurgie |
Dienstadresse: |
Campus Neuruppin
Fehrbelliner Straße 38 16816 Neuruppin Labor, N Haus |
Diensttelefon: | +49 3391 39 36911 |
Dienst-E-Mail: | Racha.ElHage@mhb-fontane.de |
An der MHB seit: | 01.12.2021 |
Forschung: | Microbiome and Disease |
EDUCATION
University of Ghent Ghent, Belgium
Oct.2014-Sep.2019
PhD in Applied Biological Sciences
● Ability of a propionate-producing synthetic microbial consortium to restore functionality in a dysbiosed human gut microbiome
Supervisors: Prof. Tom Van de Wiele, Dr. Emma Hernandez-Sanabria
University of Aberdeen, United Kingdom
Sep.2012 -August 2013
Masters of Science Degree in Molecular Nutrition
● Thesis: Ability of isolated human gut bacteria to utilize oligosaccharides from human milk
Supervisors: Dr. Karen Scott, Prof. Harry Flint, and Dr. Sylvia Duncan Honors Thesis: Second Honors degree
American University of Beirut, Lebanon
Sep.2009 – June 2011
Bachelor of Science degree in Nutrition and Dietetics
● Concentration: Therapeutic Nutrition
AWARDS
International Yakult Symposium Ghent, Belgium
Poster Award Winner April 2018
PhD Scholarship University of Ghent, Belgium
Marie Curie PhD fellowship Oct. 2014
WORK EXPERIENCE
Center for microbial ecology and Technology (Cmet) Ghent, Belgium
Oct.2014 - Sep.2019
PhD thesis
● Thesis: Ability of a propionate-producing synthetic microbial consortium to restore functionality in a dysbiosed human gut microbiome Laboratory skills:
Anaerobic and aerobic bacterial culturing including probiotics
Building bioreactors like the in vitro model system (Simulator of the human intestinal microbial ecosystem (SHIME)
VFA extraction techniques
Molecular techniques (DNA and RNA extractions, PCR, DGGE)
Plating and MIC determination (minimum inhibitory concentration)
University of Copenhagen, Denmark
Mar.2017 - Apr.2017
Testing the passage of the members of our designed propionate-producing microbial consortium in the upper GI tract specifically in The smallest Intestine (TSI) model under different conditions
ProDigest Ghent, Belgium
March 2017
Lyophilization the propionate-producing bacterial consortium and testing its survival afterwards in fed batch experiments that mimic the SHIME
American University of Beirut Medical Center, Lebanon
2013 - 2014
Research Assistant in the Department of Pediatrics and Adolescent Medicine
University of Aberdeen Aberdeen, United Kingdom
May-August 2013
Microbiology Lab:
Anaerobic culturing of gut bacteria – thin layer chromatography (TLC) –Microscopy
Mount Lebanon Hospital Beirut, Lebanon
Jul. 2011- Jan. 2012
Six months training in nutrition and dietetics field
Covered topics:
Imbalance of body weight
Diabetes and Endocrinology
Diseases of the circulatory system and Anemia
Gastroenterology
Kidney Disorders
Pulmonary Diseases
Infancy and Childhood
Tube Feeding
CONFERENCES
International Yakult Symposium Ghent, Belgium
Flash talk and poster presentation: April 2018
Ability of a propionate producing community to promote recovery from antibiotic-associated gut dysbosis
9th Probiotics, prebiotics & new foods Rome, Italy
Poster presentation: Sep. 2017
Ability of a propionate producing consortium to promote recovery from antibiotic-associated gut dysbosis
18th Gut Day Symposium Venlo, Netherland Oral Presentation: Nov. 2016
Potential of a probiotic propionate producing community to recover from the disorder caused by antibiotics
4th World Congress on targeting Microbiota Paris, France
Poster presentation: Oct. 2016
Potency of a propionate-producing microbial consortium for restoring
gut microbial functionality in gut dysbiosis
16th Gut Day symposium Amsterdam, Netherlands Attended Nov. 2014
RESEARCH TRAINING
Doctoral school courses and workshops completed:
Interphase processes of host associated microorganisms-2015
Advanced Academic English: Conference Skills - Academic Posters-2015
Leadership Foundation Course-2015
N2N Multidisciplinary Seminar Series on Bioinformatics -2014-2015.
Effective Graphical Displays -November 2015
SKILLS
Teaching: mentoring and supervision of a masters student for one year during his dissertation, in addition to teaching assistant in practical lab work in Host-microbe interaction course
Computer programs: Microsoft office: Excel, PowerPoint, and Word
Statistical software, GraphPad and Sigma Plot
Internet search engines and using Gene databases
LANGUAGES
English– speak fluently and read/write with high proficiency
Arabic– native language
French– Fair
German–A2
Supervisors: Prof. Tom Van de Wiele, Dr. Emma Hernandez-Sanabria
Masters of Science Degree in Molecular Nutrition
● Thesis: Ability of isolated human gut bacteria to utilize oligosaccharides from human milk
Supervisors: Dr. Karen Scott, Prof. Harry Flint, and Dr. Sylvia Duncan Honors Thesis: Second Honors degree
Bachelor of Science degree in Nutrition and Dietetics
● Concentration: Therapeutic Nutrition
● Thesis: Ability of a propionate-producing synthetic microbial consortium to restore functionality in a dysbiosed human gut microbiome Laboratory skills:
Anaerobic and aerobic bacterial culturing including probiotics
Building bioreactors like the in vitro model system (Simulator of the human intestinal microbial ecosystem (SHIME)
VFA extraction techniques
Molecular techniques (DNA and RNA extractions, PCR, DGGE)
Plating and MIC determination (minimum inhibitory concentration)
Microbiology Lab:
Anaerobic culturing of gut bacteria – thin layer chromatography (TLC) –Microscopy
Six months training in nutrition and dietetics field
Covered topics:
Imbalance of body weight
Diabetes and Endocrinology
Diseases of the circulatory system and Anemia
Gastroenterology
Kidney Disorders
Pulmonary Diseases
Infancy and Childhood
Tube Feeding
Flash talk and poster presentation: April 2018
Ability of a propionate producing community to promote recovery from antibiotic-associated gut dysbosis
Poster presentation: Sep. 2017
Ability of a propionate producing consortium to promote recovery from antibiotic-associated gut dysbosis
Potential of a probiotic propionate producing community to recover from the disorder caused by antibiotics
Poster presentation: Oct. 2016
Potency of a propionate-producing microbial consortium for restoring
gut microbial functionality in gut dysbiosis
Doctoral school courses and workshops completed:
Interphase processes of host associated microorganisms-2015
Advanced Academic English: Conference Skills - Academic Posters-2015
Leadership Foundation Course-2015
N2N Multidisciplinary Seminar Series on Bioinformatics -2014-2015.
Effective Graphical Displays -November 2015
Teaching: mentoring and supervision of a masters student for one year during his dissertation, in addition to teaching assistant in practical lab work in Host-microbe interaction course
Computer programs: Microsoft office: Excel, PowerPoint, and Word
Statistical software, GraphPad and Sigma Plot
Internet search engines and using Gene databases
English– speak fluently and read/write with high proficiency
Arabic– native language
French– Fair
German–A2
Publikationen
El Hage, R., Hernandez-Sanabria, E., Calatayud Arroyo, M. and Van de Wiele, T., (2020). Supplementation of a propionate-producing consortium improves markers of insulin resistance in an in vitro model of gut-liver axis. American Journal of Physiology-Endocrinology and Metabolism, 318(5), pp.E742-E749.
El Hage, R., Hernandez-Sanabria, E., Calatayud Arroyo, M., Props, R., and Van de Wiele, T. (2019) ‘’Propionate-producing consortium restores antibiotic-induced dysbiosis in a dynamic in vitro model of the human intestinal microbial ecosystem.” Frontiers in Microbiology.
El Hage, R., Hernandez-Sanabria, E. and Van de Wiele, T. (2017). Emerging Trends in “Smart Probiotics”: Functional Consideration for the Development of Novel Health and Industrial Applications. Frontiers in Microbiology, 8.
Marzorati, M., Vilchez-Vargas, R., Bussche, J., Truchado, P., Jauregui, R., El Hage, R., Pieper, D., Vanhaecke, L. and Van de Wiele, T. (2016). High-fiber and high-protein diets shape different gut microbial communities, which ecologically behave similarly under stress conditions, as shown in a gastrointestinal simulator. Molecular Nutrition & Food Research, 61(1), p.1600150.