Person

Michael Hauptmann

Prof. Dr. rer. nat. Hauptmann
Title:Prof. Dr. rer. nat.
Denomination:Biostatistics and Registry Research
Current position:Head of Institute
Specialist field:Biometrie und Registerforschung
Office address:
Medizinische Hochschule Brandenburg Theodor Fontane
Institut für Biometrie und Registerforschung
Campus Neuruppin, Haus O
Fehrbelliner Straße 38
16816 Neuruppin
Office phone number:+493391 39-14580
Office email:michael.hauptmann@mhb-fontane.de
 
Research:Statistic Methods, Registry Research
Teaching area(s):Biometrie, Statistics
Expertise in:Biostatistik, Studiendesign, statistische Methoden
Curriculum Vitae

Michael Hauptmann received a Ph.D. in Statistics from the University of Dortmund (Germany) in 1999. In the same year, he joined the Biostatistics Branch of the Division of Cancer Epidemiology and Genetics of the National Cancer Institute in Bethesda, Maryland (USA), as a postdoctoral fellow, and became a tenure-track investigator in 2004. From 2006 to 2019, Michael Hauptmann was a senior statistician and head of the Biostatistics group at the Netherlands Cancer Institute in Amsterdam (The Netherlands). Since 2019, Michael Hauptmann is a professor of Biostatistics and Registry Research at the Brandenburg Medical School in Neuruppin, Germany. Michael Hauptmann has published over 130 peer-reviewed scientific articles. He is a Statistical Editor for the Journal of the National Cancer Institute and the Journal of Clinical Oncology and is a member of the International Commission on Radiological Protection and of the Board of Advisors of the Dutch Cancer Society. For a complete CV, click here

Seit 2019 Professor für Biometrie und Registerforschung

         Medizinische Hochschule Brandenburg

2011-2019 Arbeitsgruppenleiter Biostatistik

         Netherlands Cancer Institute, Amsterdam

2004-2006 Principal Investigator

         National Cancer Institute, Bethesda, Maryland, USA

1995-1999 Doktorand (Abschluss Dr. rer. nat. Universität Dortmund)

        Helmholtz Zentrum München

1990-1995 Studium der Statistik (Abschluss Diplom)

         Universität Dortmund

Publications

Bernier MO, Baysson H, Pearce MS, Moissonnier M, Cardis E, Hauptmann M, Struelens L, Dabin J, Johansen C, Journy N, Laurier D, Blettner M, Le Cornet L, Pokora R, Gradowska P, Meulepas JM, Kjaerheim K, Istad T, Olerud H, Sovik A, Bosch de Basea M, Thierry-Chef I, Kaijser M, Nordenskjold A, Berrington de Gonzalez A, Harbron RW, Kesminiene A. The EPI-CT study: a European pooled epidemiological study to quantify the potential radiation-induced risks associated to paediatric CT-scans. Int J Epidemiol. In press.

De Boer M, Van Middelkoop M, Hauptmann M, Van der Bijl N, Bosmans J, Hendriks-Brouwer N, Schop S, De Boer JP, Overbeek LI, Lobbes MB, Klazen CA, De Jong D, Rakhorst HA, Van der Hulst RR, Van Leeuwen FE. Breast implant prevalence in the Dutch female population assessed by chest radiographs. Aesthet Surg J. In press.

Kok JL, Teepen JC, Van Leeuwen FE, Tissing WJ, Neggers SJ, Van der Pal HJ, Loonen HJ, Bresters D, Versluys B, Van den Heuvel-Eibrink MM, Van Dulmen-den Broeder E, Van der Heiden-van der Loo M, Aleman B, Daniels L, Haasbeek C, Hoeben B, Janssens G, Maduro J, Oldenburger F, Van Rij C, Tersteeg R, Hauptmann M, DCOG-LATER Study Group, Kremer LC, Ronckers CM. Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort: contributions of radiation dose, exposed cranial volume, and age. Neuro Oncol. In press.

Puppe J, Opdam M, Schouten PC, Jóźwiak K, Lips E, Severson T, Van de Ven M, Brambillasca C, Bouwman P, Van Tellingen O, Bernards R, Wesseling J, Eichler C, Thangarajah F, Malter W, Pandey GK, Ozretic L, Caldas C, Van Lohuizen M, Hauptmann M, Rhiem K, Hahnen E, Reinhardt HC, Buettner R, Mallmann P, Schoemig-Markiefka B, Schmutzler B, Linn S, Jonkers J. EZH2 is overexpressed in BRCA1-like breast tumors and predictive for sensitivity to high-dose platinum-based chemotherapy. Clin Cancer Res. In press.

Teepen JC, Kok JL, Kremer LC, Tissing WJ, Van den Heuvel-Eibrink MM, Loonen JJ, Bresters D, Van der Pal HJ, Versluys B, Van Dulmen-den Broeder E, Nijsten T, Hauptmann M, Hollema N, Dolsma WV, Van Leeuwen FE, Ronckers CM, DCOG-LATER Study Group. Long-term risk of skin cancer among childhood cancer survivors: a DCOG-LATER cohort study. J Natl Cancer Inst. In press.

Teepen JC, Kok JL, Kremer LC, Tissing WJE, Van den Heuvel-Eibrink MM, Loonen JJ, Bresters D, Van der Pal HJ, Versluys B, Van Dulmen-den Broeder E, Nijsten T, Hauptmann M, Hollema N, Dolsma WV, Van Leeuwen FE, Ronckers CM; DCOG-LATER Study Group. Long-term risk of skin cancer among childhood cancer survivors: A DCOG-LATER Cohort Study. J Natl Cancer Inst. In press.

Van den Berg MH, Overbeek A, Lambalk CB, Kaspers GJ, Bresters MM, Van den Heuvel-Eibrink MM, Kremer LC, Loonen JJ, Van der Pal HJ, Ronckers CM, Tissing WJ, Versluys AB, Van der Heiden-Van der Loo AC, Heijboer AC, Hauptmann M, Twisk JW, Laven JS, Beerendonk CC, Van Leeuwen FE, Van Dulmen-Den Broeder E, on behalf of the DCOG LATER-VEVO study group. Long-term effects of childhood cancer treatment on hormonal and ultrasound markers of ovarian function. Hum Reprod. In press.

Van der Willik KD, Hauptmann M, Jóźwiak K, Vinke EJ, Ruiter R, Stricker BH, Compter A, Ikram A, Schagen SB. Trajectories of cognitive performance prior to cancer diagnosis: a population-based study. J Natl Cancer Inst. In press.

Jacobse JN, Duane FK, Boekel NB, Schaapveld M, Hooning MJ, Seynaeve CM, Baaijens MH, Hauptmann M, Gietema JA, Aleman BM, Taylor BM, Darby BM, Van Leeuwen FE. Radiation dose-response for risk of myocardial infarction in breast cancer survivors. Int J Radiat Oncol Biol Phys 2019; 103(3): 595–604.

Kok JL, Teepen JC, Van Leeuwen FE, Tissing WJE, Neggers SJCMM, Van der Pal HJ, Loonen JJ, Bresters D, Versluys B, Van den Heuvel-Eibrink MM, Van Dulmen-den Broeder E, Van der Heiden-van der Loo M, Aleman BMP, Daniels LA, Haasbeek CJA, Hoeben B, Janssens GO, Maduro JH, Oldenburger F, Van Rij C, Tersteeg RJHA, Hauptmann M; DCOG-LATER Study Group, Kremer LCM, Ronckers CM. Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort: contributions of radiation dose, exposed cranial volume, and age. Neuro Oncol 2019; 21(3): 392–403.

Meulepas JM, Ronckers CM, Smets AM, Nievelstein RA, Gradowska P, Lee C, Jahnen A, Van Straten M, De Wit MC, Zonnenberg B, Klein WM, Merks JH, Visser O, Van Leeuwen FE, Hauptmann M. Radiation exposure from pediatric CT scans and subsequent cancer risk in the Netherlands. J Natl Cancer Inst 2019; 111(3): 256–263.

Opstal-Van Winden AW, De Haan HG, Hauptmann M, Schmidt MK, Broeks A, Russell NS, Janus CP, Krol AD, Van der Baan FH, De Bruin ML, Van Eggermond AM, Dennis J, Culver HA, Haiman CA, Sawyer EJ, Cox A, Devilee P, Hooning MJ, Peto J, Couch FJ, Pharoah P, Orr P, Easton DF, Aleman BM, Strong LC, Bhatia S, Cooke R, Robison LL, Swerdlow AJ, Van Leeuwen FE. Genetic susceptibility to radiation-induced breast cancer after Hodgkin lymphoma. Blood 2019; 133(10): 1130–1139.

Puppe J, Opdam M, Schouten PC, Jóźwiak K, Lips E, Severson T, Van de Ven M, Brambillasca C, Bouwman P, van Tellingen O, Bernards R, Wesseling J, Eichler C, Thangarajah F, Malter W, Pandey GK, Ozretić L, Caldas C, van Lohuizen M, Hauptmann M, Rhiem K, Hahnen E, Reinhardt HC, Büttner R, Mallmann P, Schömig-Markiefka B, Schmutzler R, Linn S, Jonkers J. EZH2 is overexpressed in BRCA1-like breast tumors and predictive for sensitivity to high-dose platinum-based chemotherapy. Clin Cancer Res 2019; 25(14): 4351–4362.

Spaan M, Van den Belt-Dusebout AW, Van den Heuvel-Eibrink MM, Hauptmann M, Lambalk CB, Burger CW, Van Leeuwen FE, on behalf of the OMEGA-steering group. Risk of cancer in children and young adults conceived by assisted reproductive technology. Hum Reprod 2019; 34(4): 740–750.

Akdeniz D, Schmidt MK, Seynaeve CM, McCool D, Giardiello D, Van den Broek AJ, Hauptmann M, Steyerberg EW, Hooning MJ. Risk factors for metachronous contralateral breast cancer: a systematic review and meta-analysis. Breast 2018; 44: 1–14.

Boekel NB, Jacobse JN, Schaapveld M, Hooning MJ, Gietema JA, Duane FK, Taylor CW, Darby SC, Hauptmann M, Seynaeve CM, Baaijens MH, Sonke GS, Rutgers EJ, Russell NS, Aleman BM, Van Leeuwen FE. Cardiovascular disease incidence after internal mammary chain irradiation and anthracycline-based chemotherapy for breast cancer. Br J Cancer 2018; 119: 408–418.

Dackus GM, Jóźwiak K, Sonke GS, Van der Wall E, Van Diest PJ, Hauptmann M, Siesling S, Linn SC. Optimal adjuvant endocrine treatment of ER+/HER2+ breast cancer patients by age at diagnosis: a population-based cohort study. Eur J Cancer 2018; 90: 92–101.

De Boer M, Van Leeuwen FE, Hauptmann M, Overbeek LI, De Boer JP, Hijmering NJ, Sernee A, Klazen CA, Lobbes MB, Van der Hulst RR, Rakhorst HA, De Jong D. Breast implants and the risk of anaplastic large cell lymphoma in the breast. JAMA Oncol 2018; 4(3): 335–341.

Halldorsson MO, Hauptmann M, Snabjornsson P, Haraldsdottir KH, Eiriksdottir G, Aspelund T, Guamundsson EF, Guanason V, Jonasson JG, Haraldsdottir S. The risk of developing a mismatch repair deficient colorectal cancer after undergoing cholecystectomy. Scand J Gastroenterol 2018; 53(8): 972–975.

Krul IM, Opstal-Van Winden AW, Zijlstra AW, Appelman Y, Schagen SB, Meijboom L, Serne E, Lambalk CB, Lips CB, Van Dulmen-den Broeder E, Hauptmann M, Daniels LA, Aleman BM, Van Leeuwen FE. Rationale and design of a cohort study on primary ovarian insufficiency in female survivors of Hodgkin lymphoma: influence on long-term adverse effects (SOPHIA). BMJ Open 2018; 8(9): e018120.

Lubin JH, Hauptmann M, Blair A. Indirect adjustment of an exposure with multiple categories for an unmeasured confounder. Ann Epidemiol 2018; 28(11): 801–807.

Meulepas JM, Hauptmann M, Lubin JH, Shuryak I, Brenner DJ. Is there unmeasured indication bias in radiation-related cancer risk estimates from studies of computed tomography? Radiat Res 2018; 189(2): 128–135.

Rajaraman P, Hauptmann M, Bouffler S, Wojcik A. Human individual radiation sensitivity and prospects for prediction. Ann ICRP 2018; 47(3-4): 126–141.

Teepen JC, Kok JL, Van Leeuwen FE, Tissing WJE, Dolsma WV, Van der Pal HJ, Loonen JJ, Bresters D, Versluys B, Van den Heuvel-Eibrink MM, Van Dulmen-den Broeder E, Van den Berg MH, Van der Heiden-van der Loo M, Hauptmann M, Jongmans MC, Overbeek LI, Van de Vijver MJ, Kremer LCM, Ronckers CM; DCOG-LATER Study Group. Colorectal adenomas and cancers after childhood cancer treatment: A DCOG-LATER Record Linkage Study. J Natl Cancer Inst 2018; 110(7): 758–767.

Van der Willik KD, Koppelmans V, Hauptmann M, Compter A, Ikram MA, Schagen SB. Inflammation markers and cognitive performance in breast cancer survivors 20 years after completion of chemotherapy: a cohort study. Breast Cancer Res 2018; 20(1): 135.

Van der Willik K, Ruiter R, Wolters FJ, Ikram MK, Stricker BH, Hauptmann M, Compter A, Schagen SB, Ikram MA. Mild cognitive impairment and dementia show contrasting associations with risk of cancer. Neuroepidemiology 2018; 50(3–4): 207–215.

Van Gils T, Nijeboer P, Overbeek LI, Hauptmann M, Castelijn DA, Bouma G, Mulder CJ, Van Leeuwen FE, De Jong D. Risks for lymphoma and gastrointestinal carcinoma in patients with newly diagnosed adult-onset celiac disease: consequences for follow-up. United European Gastroenterol J 2018; 6(10): 1485–1495.

Van Griethuysen JJ, Bus EM, Hauptmann M, Lahaye MJ, Maas M, Ter Beek L, Beets GL, Bakers FC, Beets-Tan RG, Lambregts DM. Gas-induced susceptibility artifacts on diffusion-weighted MRI of the rectum – effect of applying a micro-enema to improve image quality. Eur J Radiol 2018; 99: 131–137.

Wojcik A, Bouffler S, Hauptmann M, Rajaraman P. Considerations on the use of the terms radiosensitivity and radiosusceptibility. J Radiol Prot 2018; 38(3): N25–N29.

Dackus GM, Ter Hoeve ND, Opdam M, Vreuls W, Varga Z, Koop EA, Willems SM, Van Deurzen CH, Groen EJ, Cordoba-Iturriagagoitia A, Bart J, Mooyaart AL, Van den Tweel JG, Zolota V, Wesseling J, Sapino A, Chmielik E, Ryska A, Amant F, Broeks A, Kerkhoven R, Stathonikos N, Veta M, Jóźwiak K, Hauptmann M, Hoogstraat M, Wessels LF, Schmidt MK, Sonke GS, Van der Wall E, Siesling S, Van Diest PJ, Linn SC. Long-term prognosis of adjuvant treatment naive young breast cancers patients (≤40 years): the PARADIGM initiative. BMJ Open 2017; 7(11): e017842.

Gilbert E, Curtis RE, Hauptmann M, Kleinerman RA, Lynch CF, Stovall M, Smith SA, Weathers R, Andersson M, Dores GM, Fraumeni Jr JF, Fossa SD, Hall P, Hodgson DC, Holowaty EJ, Joensuu H, Johannesen TB, Langmark F, Kaijser M, Pukkala E, Rajaraman E, Storm HH, Vaalavirta L, Van den Belt-Dusebout AW, Aleman BM, Travis LB, Morton LM, Van Leeuwen FE. Stomach cancer following Hodgkin lymphoma, testicular cancer, and cervical cancer: A pooled analysis of three international studies with a focus on radiation effects. Radiat Res 2017; 187(2): 186–195.

Krul IM, Opstal–Van Winden AW, Aleman BM, Janus CP, Van Eggermond AM, De Bruin ML, Hauptmann M, Krol AD, Schaapveld M, Broeks A, Kooijman KR, Fase S, Lybeert ML, Zijlstra JM, Van der Maazen RW, Kesminiene A, Diallo I, De Vathaire F, Russell NS, Van Leeuwen FE. Breast cancer risk after radiotherapy for Hodgkin lymphoma: influence of gonadal hormone exposure. Int J Radiat Oncol Biol Phys 2017; 99(4): 843–853.

Meulepas JM, Smets AMJB, Nievelstein RAJ, Gradowska P, Verbeke J, Holscher HC, Rutten MJCM, Kieft M, Ronckers CM, Hauptmann M. Trends and patterns of computed tomography scan use among children in the Netherlands: 1990-2012. Eur Radiol 2017; 27(6): 2426–2433.

Russell NS, Van Eggermond A, Aleman A, Krul I, Cooke R, Kuiper S, Allen SD, Wallis MG, Diallo I, De Vathaire F, Hauptmann M, Swerdlow AJ, Van Leeuwen FE. Retrospective methods to estimate radiation dose at the site of breast cancer development after Hodgkin lymphoma radiotherapy. Clin Transl Rad Oncol 2017; 7: 20–27.

Teepen JC, Van Leeuwen FE, Tissing WJ, Van Dulmen-den Broeder E, Van den Heuvel-Eibrink MM, Van der Pal HJ, Loonen JJ, Bresters D, Versluys B, Neggers SJCMM, Jaspers MWM, Hauptmann M, Van der Heiden-van der Loo M, Visser O, Kremer LCM, Ronckers CM; DCOG LATER Study Group. Long-term risk of subsequent malignant neoplasms after treatment of childhood cancer in the DCOG LATER Study Cohort:  Role of chemotherapy. J Clin Oncol 2017; 35(20): 2288–2298.

Van Nimwegen FA, Ntentas G, Darby SC, Schaapveld M, Hauptmann M, Lugtenburg PJ, Janus CPM, Daniels L, Van Leeuwen FE, Cutter DJ, Aleman BMP. Risk of heart failure in survivors of Hodgkin lymphoma: effects of cardiac exposure to radiation and anthracyclines. Blood 2017; 129(16): 2257–2265.

De Ridder M, Marres CC, Smeele LE, Van den Brekel MW, Hauptmann M, Balm AJ, Van Velthuysen ML. A critical evaluation of lymph node ratio in head and neck cancer. Virchows Arch 2016; 469(6): 635–641.

Droog M, Nevedomskaya E, Kim Y, Severson T, Flach K, Opdam M, Schuurman K, Gradowska P, Hauptmann M, Dackus G, Hollema H, Mourits M, Nederlof P, Van Boven H, Linn S, Wessels LF, Van Leeuwen FE, Zwart W. Comparative cistromics reveals genomic crosstalk between FOXA1 and ERα in tamoxifen-associated endometrial carcinomas. Cancer Res 2016; 76(13): 3773–3784.

Hauptmann M, Johannesen TB, Gilbert ES, Stovall M, Van Leeuwen FE, Rajaraman P, Smith SA, Weathers RE, Aleman BM, Andersson M, Curtis RE, Dores GM, Fraumeni Jr JF, Hall P, Holowaty EJ, Joensuu H, Kaijser M, Kleinerman RA, Langmark F, Lynch CF, Pukkala E, Storm HH, Vaalavirta L, Van den Belt-Dusebout AW, Morton LM, Fossa SD, Travis LB. Increased pancreatic cancer risk following radiotherapy for testicular cancer. Br J Cancer 2016; 115: 901–908.

Kuijpers A, Hauptmann M, Aalbers A, Nienhuijs S, De Hingh I, Wiezer R, Van Ramshorst B, Van Ginkel R, Havenga K, Verwaal V. Cytoreduction and hyperthermic intraperitoneal chemotherapy: the learning curve re-assessed. Eur J Surg Oncol 2016; 42(2): 244–250.

Meulepas JM, Ronckers CM, Merks J, Weijerman ME, Lubin JH, Hauptmann M. Confounding of the association between radiation exposure from CT scans and risk of leukemia and brain tumors by cancer susceptibility syndromes. J Radiol Prot 2016; 36(4): 953–974.

Schouten PC, Vollebergh MA, Opdam M, Jonkers M, Loden M, Wesseling J, Hauptmann M, Linn SC. High expression of XIST and low expression of 53BP1 predict poor outcome after high dose alkylating chemotherapy in BRCA1-like breast cancer. Mol Cancer Therapeutics 2016; 15(1): 190–198.

Van den Belt-Dusebout AW, Spaan M, Lambalk CB, Kortman M, Laven JS, Van Santbrink EJ, Van der Westerlaken LA, Cohlen BJ, Braat DD, Smeenk JM, Land JA, Goddijn M, Van Golde RJ, Van Rumste MM, Schats R, Jóźwiak K, Hauptmann M, Rookus MA, Burger CW, Van Leeuwen FE. Association between ovarian stimulation for in vitro fertilization and long-term risk of breast cancer. JAMA 2016; 316(3): 300–312

Van Nimwegen FA, Schaapveld M, Cutter DJ, Janus CP, Krol AD, Hauptmann M, Kooijman K, Roesink J, Van der Maazen R, Darby SC, Aleman BM, Van Leeuwen FE. Radiation dose-response relationship for risk of coronary heart disease in survivors of Hodgkin lymphoma. J Clin Oncol 2016; 34(3): 235–243.

Bentin Toaldo C, Alexi X, Beelen K, Kok M, Hauptmann M, Jansen M, Berns E, Neefjes J, Linn S, Michalides R, Zwart W. Protein kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13. BMC Cancer 2015; 15: 588.

Bosch de Basea M, Pearce MS, Kesminiene A, Bernier MO, Dabin J, Engels H, Hauptmann M, Krille L, Meulepas JM, Struelens L, Baatout S, Kaijser M, Maccia C, Jahnen A, Thierry-Chef I, Blettner M, Johansen C, Kjaerheim K, Nordenskj¨old A, Olerud H, Salotti JA, Andersen TV, Vrijheid M, Cardis E. EPI-CT: Design, challenges and epidemiological methods of an international study on cancer risk after paediatric CT. J Radiol Prot 2015; 35(3): 611–628.

Cutter D, Schaapveld M, Darby SC, Hauptmann M, Van Nimwegen FA, Krol SA, Janus C, Van Leeuwen FE, Aleman BM. Risk of valvular heart disease after radiotherapy for Hodgkin lymphoma. J Natl Cancer Inst 2015; 107(4).

Groenendijk FH, Mellema WW, Van der Burg E, Schut E, Hauptmann M, Horlings HM, Willems SM, Van den Heuvel MM, Jonkers J, Smit EF, Bernards R. Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation. Int J Cancer 2015; 136(6): 1434–1444.

Hauptmann M, Fossa SD, Stovall M, Van Leeuwen FE, Johannesen TB, Rajaraman P, Gilbert ES, Smith SA, Weathers RE, Aleman BM, Andersson M, Curtis RE, Dores GM, Fraumeni Jr JF, Hall P, Holowaty EJ, Joensuu H, Kaijser M, Kleinerman RA, Langmark F, Lynch CF, Pukkala E, Storm HH, Vaalavirta L, Van den Belt-Dusebout AW, Travis LB, Morton LM. Increased stomach cancer risk following radiotherapy for testicular cancer. Br J Cancer 2015; 112(1): 44–51.

Krul IM, Groeneveld E, Spaan M, Van den Belt-Dusebout AW, Mooij TM, Hauptmann M, Twisk JW, Lambers MJ, Hompes PG, Burger CW, Lambalk CB, Van Leeuwen FE on behalf of the OMEGA-project group. Increased breast cancer risk in IVF treated women with a multiple pregnancy: a new hypothesis based on old IVF treatment data. Eur J Cancer 2015; 51(1): 112–120.

Kuijpers AM, Aalbers AG, Nienhuijs SW, De Hingh IH, Wiezer MJ, Van Ramshorst B, Van Ginkel RJ, Havenga K, Heemsbergen WD, Hauptmann M, Verwaal VJ. Implementation of a standardized HIPEC protocol improves outcome for peritoneal malignancy. World J Surg 2015; 39(2): 453–460.

Pearce N, Blair A, Vineis P, Anto J, Armstrong B, Attfield M, Baccarelli A, Beane Freeman L, Beland F, Berrington A, Bertazzi P, Birmbaum L, Bucher J, Cardis E, Cherrie J, Christiani D, Cocco P, Coggon D, Comba P, Demers P, Dement J, Douwes J, Engel L, Fletcher T, Fontham E, Forastiere F, Friesen M, Fritschi L, Gerin M, Goldberg M, Grandjean P, Gustavsson P, Hartge P, Hansen J, Hauptmann M, Heederick D, Hoppin J, Huff J, Jarvholm B, Karagas M, Kjuus H, Kogevinas M, Kriebel D, Kristensen P, Kromhout H, Laden F, Lebailly P, Lemasters G, Lubin J, Lynch C, Lynge E, ´ Mannetje A, McLaughlin J, Merchant J, Merletti F, Miller A, Parent ME, Perry M, Pesatori A, Pirastu R, Porta M, Pukkala E, Rice C, Ritz B, Ruder A, Rushton L, Rusyn I, Samet J, De Sanjose S, Saracci R, Schernhammer E, Schulte P, Sexias N, Silvermann D, Simonato L, Smith A, Spinelli J, Stayner L, Steenland K, Stenzel T, Stewart B, Stewart T, Symanski E, Terracini B, Vainio H, Vena J, Vermeulen R, Victora C, Wagner G, Ward E, Weinberg C, Weisenburger D, Whelan B, Zahm S, Zhang Y. Evidence assessment for Public Health: the 40 years work of the IARC Monographs. Environ Health Persp 2015; 123(6): 507–514.

Schouten PC, Marme F, Aulmann S, Sinn HP, Van Essen HJ, Ylstra B, Hauptmann M, Schneeweiss A, Linn SC. Breast cancers with a BRCA1-like DNA copy number profile recur less often than expected after high-dose alkylating chemotherapy. Clin Cancer Res 2015; 21(4): 763–770.

Theunissen EA, Zuur CL, Jóźwiak K, Lopez-Yurda M, Hauptmann M, Rasch CR, Van der Baan S, De Boer JP, Dreschler WA, Balm AJ. Prediction of hearing loss due to cisplatin chemoradiotherapy. JAMA Otolaryngol Head Neck Surg 2015; 141(9): 810–815.

Theunissen EA, Zuur CL, Bosma SC, Lopez Yurda M, Hauptmann M, Van der Baan S, De Boer JP, Van der Molen L, Rasch CR, Dreschler WA, Balm AJ. Long-term hearing loss after chemoradiation in patients with head and neck cancer. Laryngoscope 2014; 124(12): 2720–2725.

Vollebergh MA, Lips EH, Nederlof PM, Wessels LF, Wesseling J, Van de Vijver MJ, De Vries EG, Van Tinteren H, Jonkers J, Hauptmann M, Rodenhuis S, Linn SC. Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict benefit of intensified carboplatin-based chemotherapy. Breast Cancer Res 2014; 16(3): R47.

Meulepas JM, Ronckers CM, Smets AM, Nievelstein RA, Jahnen A, Lee C, Kieft M, Lameris JS, Van Herk M, Greuter MJ, Jeukens CR, Van Straten M, Visser O, Van Leeuwen FE, Hauptmann M. Leukemia and brain tumors among children after radiation exposure from CT scans: design and methodological opportunities of the Dutch Pediatric CT Study. Eur J Epidemiol 2014; 29(4): 293–301.

Kuijpers AM, Mehta AM, Boot H, Van Leerdam ME, Hauptmann M, Aalbers AG, Verwaal VJ.  Perioperative systemic chemotherapy in peritoneal carcinomatosis of lymph node positive colorectal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Ann Oncol 2014; 25(4): 864–869.

Marres CC, De Ridder MD, Hegger I, Van Velthuysen ML, Hauptmann M, Navran A, Balm AJ. The influence of nodal yield in neck dissections on lymph node ratio in head and neck cancer. Oral Oncol 2014; 50(1): 59–64.

Morton LM, Dores GM, Curtis RE, Lynch CF, Stovall M, Hall P, Gilbert ES, Aleman BM, Hodgson DC, Storm HH, Johannesen TB, Smith SA, Weathers RE, Andersson M, Fossa SD, Hauptmann M, Holowaty EJ, Joensuu H, Kaijser M, Kleinerman RA, Langmark F, Pukkala E, Vaalavirta L, Van den Belt-Dusebout AW, Fraumeni Jr. JF, Travis LB, Van Leeuwen FE. Stomach cancer risk after treatment for Hodgkin lymphoma. J Clin Oncol 2013; 31(27): 3369–3377.

Stiekema J, Cats A, Kuijpers A, Van Coevorden F, Boot H, Jansen EP, Verheij M, Balague Ponz O, Hauptmann M, Van Sandick JW. Surgical treatment results of intestinal and diffuse type gastric cancer. Implications for a differentiated therapeutic approach? Eur J Surg Oncol 2013; 39(7): 686–693.

Beelen K, Opdam M, Severson T, Koornstra RH, Vincent AD, Hauptmann M, Van Schaik RH, Berns EM, Vermorken JB, Van Diest PJ, Linn SC. CYP2C19*2 predicts substantial tamoxifen benefit in postmenopausal breast cancer patients randomized between adjuvant tamoxifen versus no systemic treatment. Breast Cancer Res Treat 2013; 139(3): 649–655.

Beane Freeman LE, Blair A, Lubin JH, Stewart PA, Hayes RB, Hoover RN, Hauptmann M. Mortality from solid tumors among workers in formaldehyde industries: an update of the NCI cohort. Am J Ind Med 2013; 56: 1015–1026.

Schouten PC, Van Dyk E, Braaf LM, Mulder L, Lips EH, De Ronde JJ, Holtman L, Wesseling J, Hauptmann M, Wessels LF, Linn SC, Nederlof PM. Platform comparisons for identification of breast cancers with a BRCA-like copy number profile. Breast Cancer Res Treat 2013; 139(2): 317–327.

Lodder WL, Lange CA, Van Velthuysen ML, Hauptmann M, Balm AJ, Van den Brekel MW, Pameijer FA. Can extranodal spread in head and neck cancer be detected on MR imaging. Oral Oncol 2013; 49(6): 626–633.

Van Monsjou HS, Lopez-Yurda M, Hauptmann M, Van den Brekel MW, Balm AJ, Wreesmann VB. Oral and oropharyngeal squamous cell carcinoma in young patients: The Netherlands Cancer Institute experience. Head Neck 2013; 35(1): 94–102.

Pijpe A, Andrieu N, Easton DF, Kesminiene A, Cardis E, GENEPSO, Nogues C, Gauthier-Villars M, Lasset C, Fricker JP, EMBRACE, Peock S, Frost D, Evans DG, Eeles RA, Paterson J, HEBON, Manders P, Van Asperen CJ, Ausems MG, Meijers-Heijboer H, Thierry-Chef I, Hauptmann M, Goldgar D, Rookus MA, Van Leeuwen FE. Diagnostic radiation exposure and breast cancer risk in BRCA1/2 mutation carriers in the GENE-RAD-RISK study. BMJ 2012; 345: e5660.

Kok M, Koornstra RH, Mook S, Hauptmann M, Fles R, Simon I, Glas A, Jansen MP, Berns EM, Foekens JA, Linn SC, Van ’t Veer LJ. Additional value of 70-gene signature and levels of ER and PR for the prediction of outcome in tamoxifen-treated ER-positive breast cancer. Breast 2012; 21: 769–778.

Kreeft AM, Smeele LE, Rasch CR, Hauptmann M, Rietveld DH, Leemans CR, Balm AJ. Preoperative imaging and surgical margins in maxillectomy patients. Head Neck 2012; 34(11): 1652–1656.

Ackerstaff AH, Rasch CR, Balm AJ, De Boer JP, Wiggenraad R, Rietveld DH, Gregor RT, Kroger R, Hauptmann M, Vincent A, Hilgers FJ. Five-year quality of life results of the randomized clinical phase III (RADPLAT) trial, comparing concomitant intra-arterial versus intravenous chemoradiotherapy in locally advanced head and neck cancer. Head Neck 2012; 34(7): 974–980.

Vollebergh MA, Lips EH, Nederlof PM, Wessels LF, Schmidt MK, Van Beers EH, Cornelissen S, Holtkamp M, Froklage FE, De Vries EG, Schrama JG, Wesseling J, Van de Vijver MJ, Van Tinteren H, De Bruin M, Hauptmann M, Rodenhuis S, Linn SC. An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients. Ann Oncol 2011; 22(7): 1561–1570.

Molloy TJ, Devriese LA, Helgason HH, Bosma AJ, Hauptmann M, Voest EE, Schellens JH, Van’t Veer LJ. A multi-marker QPCR-based platform for the detection of circulating tumor cells in patients with early-stage breast cancer. Br J Cancer 2011; 104(12): 1913–1919.

Knegjens JL, Pameijer FA, Hauptmann M, Balm AJ, Hoebers FJ, De Bois JA, Kaanders JH, Verhoef LC, Wijers OB, Wiggenraad RG, Buter J, Rasch CR. Tumor volume as outcome predictor in hemoradiation for advanced head and neck cancer. Head Neck 2011; 33(3): 375–382.

Kok M, Zwart W, Holm C, Fles R, Hauptmann M, Van ’t Veer LJ, Wessels LF, Neefjes J, Stal O, Linn SC, Landberg G, Michalides R. PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer. Breast Cancer Res Treat 2011; 125: 1–12.

Vollebergh MA, Kappers I, Klomp HM, Buning-Kager JC, Korse CM, Bonfrer JM, Hauptmann M, De Visser KE, Van den Heuvel MM, Linn SC. Ligands of epidermal growth factor receptor and the insulinlike growth factor family as serum biomarkers for response to epidermal growth factor receptor inhibitors in patients with advanced non-small cell lung cancer. J Thorac Oncol 2010; 5(12): 1939–1948.

Borst GR, Ishikawa M, Nijkamp J, Hauptmann M, Shirato H, Bengua G, Onimaru R, De Bois JA, Lebesque JV, Sonke JJ. Radiation pneumonitis after hypofractionated radiotherapy: evaluation of the LQ(L) model and different dose parameters. Int J Radiat Oncol Biol Phys 2010; 77(5): 1596–1603.

Van der Pal HJ, Van Dalen EC, Hauptmann M, Kok WE, Caron HN, Van den Bos C, Oldenburger F, Koning CC, Van Leeuwen FE, Kremer LC. Cardiac function in 5-year survivors of childhood cancer: a long-term follow-up study. Arch Intern Med 2010; 170(14): 1247–1255.

Knauer M, Mook S, Rutgers EJ, Bender RA, Hauptmann M, Van de Vijver M, Koornstra RH, Buenode- Mesquita JM, Linn SC, Van ’t Veer LJ. The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer. Breast Cancer Res Treat 2010; 120(3): 655–661.

De Jong MC, Pramana J, Knegjens JL, Balm AJ, Van den Brekel MW, Hauptmann M, Begg AC, Rasch CR. HPV and high risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer independent of clinical factors. Radiother Oncol 2010; 95(3): 365–370.

Rasch CR, Hauptmann M, Schornagel J, Wijers O, Buter J, Gregor T, Wiggenraad R, De Boer JP, Ackerstaff AH, Kroger R, Hoebers FJ, Balm AJ. Intra-arterial versus intravenous chemoradiation for advanced head and neck cancer: results of a randomized phase III trial. Cancer 2010; 116(9): 2159–2165.

Retel VP, Joore MA, Knauer M, Linn SC, Hauptmann M, Van Harten WH. Cost-effectiveness of the 70-gene signature versus Sankt Gallen guidelines and Adjuvant Online for early breast cancer. Eur J Cancer 2010; 46(8): 1382–1391.

Brown LM, Gridley G, Wu AH, Falk RT, Hauptmann M, Kolonel LN, West DW, Nomura AMY, Pike MC, Hoover RN, Ziegler RG. Low level alcohol intake, cigarette smoking and risk of breast cancer in Asian-American women. Breast Cancer Res Treat 2010; 120: 203–210.

Zhang L, Tang X, Rothman N, Vermeulen R, Ji Z, Shen M, Qiu C, Guo W, Liu S, Reiss B, Beane Freeman L, Ge Y, Hubbard AE, Hua M, Blair A, Galvan N, Ruan X, Alter BP, Xin KX, Li S, Moore LE, Kim S, Xie Y, Hayes RB, Azuma M, Hauptmann M, Xiong J, Stewart PA, Li L, Rappaport SM, Huang H, Fraumeni Jr. JF, Smith MT, Lan Q. Occupational exposure to formaldehyde, hematotoxicity and leukemia-specific chromosome changes in cultured myeloid progenitor cells. Cancer Epidemiol Biomarkers Prev 2010; 19: 80–88.

Kok M, Holm-Wigerup C, Hauptmann M, Michalides R, Stal O, Linn S, Landberg G. Estrogen receptor- α phosphorylation at serine-118 and tamoxifen response in breast cancer. J Natl Cancer Inst 2009; 101: 1725–1729.

Hauptmann M, Stewart PA, Lubin JH, Beane Freeman LE, Hornung RW, Herrick RF, Hoover RN, Fraumeni JF Jr, Blair A, Hayes RB. Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde in the funeral industry. J Natl Cancer Inst 2009; 101: 1696–1708.

Van den Belt-Dusebout AW, Aleman BM, Besseling G, De Bruin ML, Hauptmann M, Van ’t Veer MB, De Wit R, Ribot JG, Noordijk EM, Kerst JM, Gietema JA, Van Leeuwen FE. Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy. Int J Radiat Oncol Biol Phys 2009; 75: 1420–1429.

Borst GR, Ishikawa M, Nijkamp J, Hauptmann M, Shirato H, Onimaru R, Van den Heuvel MM, Belderbos J, Lebesque JV, Sonke JJ. Radiation pneumonitis in patients treated for malignant pulmonary lesions with hypofractionated radiation therapy. Radiother Oncol 2009; 91: 307–313.

Beane Freeman LE, Blair A, Lubin JH, Stewart PA, Hayes RB, Hoover RN, Hauptmann M. Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries: update of the NCI cohort. J Natl Cancer Inst 2009; 101: 751–761.

Wildeman MA, Gibcus JH, Hauptmann M, Begg AC, Van Velthuysen ML, Hoebers FJ, Mastik MF, Schuuring E, Van der Wal JE, Van den Brekel MW. Radiotherapy in laryngeal carcinoma: can a panel of 13 markers predict response? Laryngoscope 2009; 119: 316–322.

Holm C, Kok M, Michalides R, Fles R, Koornstra RH, Wesseling J, Hauptmann M, Neefjes J, Peterse JL, Stal O, Landberg G, Linn SC. Phosphorylation of the oestrogen receptor alpha at serine 305 and prediction of tamoxifen resistance in breast cancer. J Pathol 2009; 217: 372–379.

Pietersen AM, Horlings HM, Hauptmann M, Langerod A, Ajouaou A, Cornelissen-Steijger P, Wessels LF, Jonkers J, Van de Vijver MJ, Van Lohuizen M. EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer. Breast Cancer Res 2009; 10: R109.

Kok M, Linn SC, Van Laar RK, Jansen MP, Van den Berg TM, Delahaye LJ, Glas AM, Peterse JL, Hauptmann M, Foekens JA, Klijn JG, Wessels LF, Van ’t Veer LJ, Berns EM. Comparison of gene expression profiles predicting progression in breast cancer patients treated with tamoxifen. Breast Cancer Res Treat 2009; 113: 275–283.

Hooning MJ, Aleman BM, Hauptmann M, Baaijens MH, Klijn JG, Noyon R, Stovall M, Van Leeuwen FE. Roles of radiotherapy and chemotherapy in the development of contralateral breast cancer. J Clin Oncol 2008; 26: 5561–5568.

Berhane K, Hauptmann M, Langholz B. Using tensor product splines in modeling exposure-timeresponse relationships: application to the Colorado Plateau uranium miners cohort. Stat Med 2008; 27: 5484–5496.

Weigelt B, Horlings HM, Kreike B, Hayes MM, Hauptmann M, Wessels LF, De Jong D, Van de Vijver MJ, Van ’t Veer LJ, Peterse JL. Refinement of breast cancer classification by molecular haracterization of histological special types. J Pathol 2008; 216: 141–150.

Chodick G, Bekiroglu N, Hauptmann M, Alexander BH, Freedman DM, Doody MM, Cheung LC, Simon SL, Weinstock RM, Bouville A, Sigurdson AJ. Risk of cataract after exposure to low doses of ionizing radiation: a 20-year prospective cohort study among US radiologic technologists. Am J Epidemiol 2008; 168: 620–631.

Sigurdson AJ, Ha M, Hauptmann M, Bhatti P, Sram R, Beskid O, Tawn EJ, Whitehouse CA, Lindholm C, Nakano M, Kodama Y, Nakamura N, Vorobstova I, Oestreicher U, Stephan G, Yong LC, Bauchinger M, Schmid E, Chung HW, Darroudi F, Roy L, Voisin P, Barquinero JF, Livingston G, Blakey D, Hayata I, Zhang W, Wang C, Bennett LM, Littlefield LG, Edwards AA, Kleinerman RA, Tucker JD. International study of factors affecting human chromosome translocations. Mutat Res 2008; 652: 112–121.

Ji BT, Blair A, Shu XO, Dosemeci M, Hauptmann M, Yang G, Chow WH, Lubin JH, Gao YT, Rothman N, Zheng W. Occupation and breast cancer risk among Shanghai women in a population-based cohort study. Am J Ind Med 2008; 51: 100–110.

De Bruin ML, Huisbrink J, Hauptmann M, Kuenen MA, Ouwens GM, Van ’t Veer MB, Aleman BM, Van Leeuwen FE. Treatment-related risk factors for premature menopause following Hodgkin lymphoma. Blood 2008; 111: 101–108.

Bhatti P, Struewing JP, Alexander BH, Hauptmann M, Bowen L, Mateus-Pereira LH, Pineda MA, Simon SL, Weinstock RM, Rosenstein M, Stovall M, Preston DL, Linet MS, Doody MM, Sigurdson AJ. Polymorphisms in DNA repair genes, ionizing radiation exposure and risk of breast cancer in U.S. radiologic technologists. Int J Cancer 2008; 122: 177–182.

Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM, Ajouaou A, Beelen K, Linn SC, Gonzalez-Angulo AM, Stemke-Hale K, Hauptmann M, Beijersbergen RL, Mills GB, Van de Vijver MJ, Bernards R. A functional genetic approach identifies the PI3K pathway as a major determinant of Trastuzumab resistance in breast cancer. Cancer Cell 2007; 12: 395–402.

Sigurdson AJ, Bhatti P, Doody MM, Hauptmann M, Bowen L, Simon SL, Weinstock RM, Linet MS, Rosenstein M, Stovall M, Alexander BH, Preston DL, Struewing JP, Rajaraman P. Polymorphisms in apoptosis- and proliferation-related genes, ionizing radiation exposure, and risk of breast cancer among U.S. radiologic technologists. Cancer Epidemiol Biomarkers Prev 2007; 16: 2000–2007.

Lubin JH, Caporaso N, Alavanja M, Wichmann HE, Schaffrath-Rosario A, Krewski D, Zielinski JM, Brownson R, Field RW, Letourneau EG, Lynch CF, Sandler DP, Schoenberg JB, Wilcox HB, Kleinerman R, Wang Z, Hauptmann M, Langholz B, Hartge P, Garcia-Closas M, Hayes RB, Silverman DT, Brown LM. Cigarette smoking and cancer: modeling total exposure and intensity. Am J Epidemiol 2007; 166: 479–89.

Ha M, Mabuchi K, Sigurdson AJ, Freedman MD, Linet MS, Doody MM, Hauptmann M. Smoking cigarettes before first childbirth increases risk of breast cancer. Am J Epidemiol 2007; 166: 55–61.

Bhatti P, Preston DL, Doody MM, Hauptmann M, Kampa D, Alexander BH, Petibone D, Simon SL, Weinstock RM, Bouville A, Yong LC, Freedman DM, Mabuchi K, Linet MS, Edwards AA, Tucker JD, Sigurdson AJ. Retrospective biodosimetry among United States radiologic technologists. Radiat Res 2007; 167: 727–734.

Krstev S, Ji BT, Shu XO, Blair A, Zheng W, Lubin JH, Vermeulen R, Hauptmann M, Rothman N, Gao YT, Mustafa D, Chow WH. Occupation and adult-onset asthma among Chinese women in a population-based cohort. Am J Ind Med 2007; 50: 265–273.

Van den Broeck GB, Balm AJM, Van den Brekel MWM, Hauptmann M, Schornagel JH, Rasch CRN. Relationship between clinical factors and the incidence of toxicity after intra-arterial chemoradiation for head and neck cancer. Radiother Oncol 2006; 81: 143–150.

Rajaraman P, Sigurdson AJ, Doody MM, Freedman DM, Hauptmann M, Alexander BH, Linet MS. Lung cancer incidence among U.S. radiologic technologists, 1983–1998. Int J Cancer 2006; 119: 2481– 2486.

Zabel EW, Alexander BH, Mongin SJ, Doody MM, Sigurdson AJ, Linet MS, Freedman DM, Hauptmann M, Mabuchi K, Ron E. Thyroid cancer and employment as a radiologic technologist. Int J Cancer 2006; 119: 1940–1945.

Linet MS, Hauptmann M, Freedman DM, Alexander BH, Miller J, Sigurdson AJ, Doody MM. Interventional radiography and mortality risks in U.S. radiologic technologists. Pediatr Radiol 2006; 36:113–120.

Doody MM, Freedman DM, Alexander BH, Hauptmann M, Rao RS, Miller J, Mabuchi K, Ron E, Sigurdson AJ, Linet MS. Breast cancer incidence in U.S. radiologic technologists. Cancer 2006; 106: 2707–2715.

Simon SL, Weinstock RM, Doody MM, Neton J, Wenzel T, Stewart P, Mohan AK, Yoder C, Freedman M, Hauptmann M, Ron E, Bouville A, Feng A, Cardarelli J, Utterback D, Linet M. Estimating historical radiation doses to a cohort of U.S. radiologic technologists. Radiat Res 2006; 166: 174–192.

Linet MS, Freedman DM, Mohan AK, Doody MM, Ron E, Mabuchi K, Alexander BH, Sigurdson A, Hauptmann M. Incidence of hematopoietic malignancies in U.S. radiologic technologists. Occup Environ Med 2005; 62: 861–867.

Sigurdson AJ, Hauptmann M, Alexander BH, Doody MM, Thomas CB, Struewing JP, Jones IM. DANN damage among thyroid cancer and multiple cancer cases, controls, and long-lived individuals. Mut Res 2005; 586: 173–188.

Cogliano VJ, Grosse Y, Baan RA, Straif K, Secretan MB, Ghissassi FE, and the Working Group for Volume 88. Summary of IARC Monographs on Formaldehyde, 2-Butoxyethanol, and 1-tert-Butoxy-2- Propanol. Environ Health Persp 2005; 113: 1205–1208.

Peters A, von Klot S, Heier M, Trentinaglia I, Cyrys J, H¨ormann A, Hauptmann M, Wichmann HE, Löwel H. Particulate air pollution and nonfatal cardiac events. Part I. Air pollution, personal activities, and onset of myocardial infarction in a case-crossover study. Res Rep Health Eff Inst 2005; 124: 1–66.

Yoshinaga S, Hauptmann M, Sigurdson AJ, Doody MM, Freedman DM, Alexander BH, Linet MS, Ron E, Mabuchi K. Non-melanoma skin cancer in relation to ionizing radiation exposure among U.S. radiologic technologists. Int J Cancer 2005; 115: 828–834.

Hauptmann M, Lubin JH, Hayes RB, Stewart P, Blair A. Mortality from solid cancers among industrial workers exposed to formaldehyde. Am J Epidemiol 2004; 159: 1117–1130.

Sigurdson AJ, Hauptmann M, Chatterjee N, Alexander BH, Doody MM, Rutter JL, Struewing JP. Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes. BMC Cancer 2004; 4:9.

Travis LB, Hauptmann M, Gaul LK, Storm HH, Goldman MB, Nyberg U, Berger E, Janower ML, Hall P, Monson RR, Holm LE, Land CE, Schottenfeld D, Boice JD Jr, Andersson M. Site-specific cancer incidence and mortality after cerebral angiography with or without radioactive thorotrast. Radiat Res 2003; 160: 691–706.

Hauptmann M, Lubin JH, Hayes RB, Stewart P, Blair A. Mortality from lymphohematopoietic malignancies among workers employed in formaldehyde industries. J Natl Cancer Inst 2003; 95: 1615–1623.

Sigurdson AJ, Doody MM, Rao RS, Freedman DM, Alexander BH, Hauptmann M, Mohan AK, Yoshinaga S, Hill DA, Tarone R, Mabuchi K, Ron E, Linet MS. Cancer incidence in the U.S. radiologic technologists Health Study, 1983–1998. Cancer 2003; 97: 3080–3089.

Hauptmann M, Mohan AK, Doody MM, Linet MS, Mabuchi K. Mortality from diseases of the circulatory system in U.S. radiologic technologists. Am J Epidemiol 2003; 157: 239–248.

Freedman DM, Sigurdson AJ, Rao RS, Hauptmann M, Alexander BH, Mohan AK, Doody MM, Linet MS. Risk of melanoma among radiologic technologists in the United States. Int J Cancer 2003; 103: 556–562.

Mohan AK, Hauptmann M, Freedman DM, Ron E, Matanoski GM, Lubin JH, Alexander BH, Boice JD, Doody MM, Linet MS. Cancer and other causes of mortality among radiologic technologists in the United States. Int J Cancer 2003; 103: 259–267.

Walcott FL, Hauptmann M, Duphorne CM, Pillow PC, Strom SS, Sigurdson AJ. A case-control study of dietary phytoestrogens and testicular cancer risk. Nutr Cancer 2002; 44: 44–51.

Mohan AK, Hauptmann M, Linet MS, Ron E, Lubin JH, Freedman DM, Alexander BH, Boice JD, Doody MM, Matanoski GM. Breast cancer mortality among radiologic technologists in the United States. J Natl Cancer Inst 2002; 94: 943–948.

Hauptmann M, Pohlabeln H, Lubin JH, J¨ockel KH, Ahrens W, Br¨uske-Hohlfeld I, Wichmann HE. The exposure-time-response-relationship between occupational asbestos exposure and lung cancer in two German case-control studies. Am J Ind Med 2002; 41: 89–97.

Hauptmann M, Berhane K, Langholz B, Lubin JH. Using splines to analyse latency in the Colorado Plateau uranium miners cohort. J Epidemiol Biostat 2001; 6: 417–424.

Hauptmann M, Wellmann J, Lubin JH, Rosenberg PS, Kreienbrock L. The analysis of exposure-timeresponse relationships using a spline weight function. Biometrics 2000; 56: 1105–1108.

Hauptmann M, Lubin JH, Rosenberg PS, Wellmann J, Kreienbrock L. The use of sliding time windows for the exploratory analysis of temporal effects of smoking histories on lung cancer risk. Stat Med 2000; 19: 2185–2194.