Neuruppin, 3 March 2025
Earlier this year, Sandy Burmeister, statistician at the Institute of Biostatistics and Registry Research, Brandenburg Medical School Theodor Fontane (MHB) in Neuruppin (director: Prof. Dr. Michael Hauptmann), published results of a study on a preliminary stage of breast cancer, the Ductal Carcinoma in Situ (DCIS). The analysis of data from 3,424 patients diagnosed with DCIS between 2004 and 2020 registered in Brandenburg-Berlin revealed a notable trend in de-escalating treatment. This means that more intensive types of treatment like surgery or radiotherapy were given up over time. Comparison of different treatment types did not show significant differences in the development of DCIS towards invasive breast cancer, so that less aggressive treatment options for this pre-cancerous stage appear to be reasonable.
Other partners in the collaboration project: the clinical cancer registry Brandenburg-Berlin (Dr. Constanze Schneider, Dr. Anne von Rüsten), the radiotherapy department at the Universitätsklinikum Ruppin-Brandenburg (ukrb) in Neuruppin (director: Dr. André Buchali), the obstetrics and gynecology department at the clinical center Frankfurt/Oder (director: Prof. Dr. Christiane Richter-Ehrenstein) and the MHB Institute of Social Medicine and Epidemiology (director: Prof. Dr. Christine Holmberg). The team of researchers plans to confirm and expand their findings with a considerably larger patient cohort from several German federal states.
For more details see: Burmeister S, Jóźwiak K, Richter-Ehrenstein C, Buchali A, Holmberg C, von Rüsten A, Schneider C, Hauptmann M. Treatment and Outcome of Ductal Carcinoma in Situ for the German Federal States Berlin and Brandenburg in the Period 2007–2020. GebFra Science 2025. doi: 10.1667/RADE-24-00226.1.
