Publikationen aus der MHB zu den Themen Therapie-Deeskalation und Überversorgung in der Medizin
2026
Banys-Paluchowski M, Hartmann S, de Boniface J, Gentilini OD, Ditsch N, Stickeler E, Karadeniz Cakmak G, Hauptmann M, Schroth J, Thill M, di Micco R, Hahn M, Murawa D, Rubio IT, Pinto D, Kontos M, Niinikoski L, Gasparri ML, Nina H, Rebaza LP, Fröhlich S, Schmidt E, Wihlfahrt K, Berger T, Basali T, Ruf F, Rief A, Bonci EA, Peintinger F, Schlichting E, Valiyeva Qanimat H, Vanhoeij M, Kadayaprath G, Dostalek L, Kothari A, Perhavec A, Ivanov T, Zippel D, Adamczyk B, Porpiglia M, Gürleyik GM, Untch M, Lux MP, Jursik K, Kolberg HC, Reimer T, Tauber N, Rody A, Matrai Z, Krawczyk N, Thongvitokomarn S, Kühn T. Marking Techniques for Target Lymph Nodes in Node-Positive Breast Cancer Treated With Neoadjuvant Therapy in the AXSANA/EUBREAST-03/AGO-B-053 Study. J Clin Oncol. 2026 Mar;44(7):575-585.
Beeker, T., & Pisl, V. (2026). Indication is Key to Prevent Inverse Care. The American Journal of Bioethics, 26(2), 61–63.
Pisl, V., Starcevic, V., Horacek, J., Vevera, J., Beeker, T. (2026) Beyond awareness: mental health promotion requires epistemic diversity, not pathologization. Frontiers in Psychiatry (accepted).
Te Meerman, S., Veldmeijer, L., Beeker, T. (2026) Ian Hacking's looping effect and the psychiatrization of society: A five-step model. Philosophical Psychology (under review).
2025
Boersma LJ, Hessels A, Roberti S, Seravalli E, Bijker N, Coppes RP, Crijns APG, Daniels L, Eekers DBP, Essers M, van Gestel CMJ, Heemsbergen W, Hoogeman M, Immink M, Klaver YLB, Kroesen M, Langendijk JA, Maduro JH, Niezink AGH, Petoukhova AL, Russell NS, Sattler MGA, van der Schaaf A, Schuit E, Ta B, Verhoeven K, Hauptmann M, van Leeuwen F. Selection of patients for proton therapy to reduce risk of second primary lung and breast cancer. Radiother Oncol. 2025 Sep;210:110998.
Burmeister, S., Jóźwiak, K., Richter-Ehrenstein, C., Buchali, A., Holmberg, C., von Rüsten, A., Schneider, C., Hauptmann, M. (2025) Treatment and Outcome of Ductal Carcinoma in Situ for the German Federal States Berlin and Brandenburg in the Period 2007-2020. Geburtshilfe und Frauenheilkunde;2025;85(6):620-30.
Caramenti L, Wołowiec P, Kędzierawski P, Góźdź S, Buchali A, Hauptmann M, Wojcik A. Individual Sensitivity for Radiotherapy-related Adverse Tissue Reactions in Patients Treated Twice for Metachronous Cancers. Radiat Res. 2025 Feb 1;203(2):107-114.
Diekhoff, T., Poddubnyy, D. (2025) The imaging crisis in axial spondyloarthritis. Lancet Rheumatology. 2025; 7(9), e652-e656
Koch T., von Peter S., Weinmann S., Ruiz-Pérez G. (2025) Self-reported attitudes and strategies of physicians towards medication reduction and discontinuation. Psychiatry Researchg, 352: 116685
Kühn T, Banys-Paluchowski M, Ditsch N, Stickeler E, Hauptmann M, Schroth J, Karadeniz Cakmak G, Hahn M, Thill M, Reimer T, Fröhlich S, Schmidt E, Wihlfahrt K, Berger T, Basali T, Ruf F, Rief A, Lux MP, Kolberg HC, Rubio IT, Gasparri ML, Kontos M, Bonci EA, Niinikoski L, Murawa D, Pinto D, Peintinger F, Schlichting E, Nina H, Valiyeva Qanimat H, Vanhoeij M, Rebaza LP, Aktas Sezen B, Jursik K, Kadayaprath G, Dostalek L, Kothari A, Perhavec A, Ivanov T, Zippel D, Thongvitokomarn S, Gurleyik MG, Watermann D, Porpiglia M, Lebeau A, Di Micco R, Gentilini OD, de Boniface J, Hartmann S; AXSANA Study Group. Axillary dissection for low-volume nodal involvement after neoadjuvant therapy in breast cancer: multicentre AXSANA cohort study. Br J Surg. 2025 Sep 2;112(9):znaf180.
Radner M, Burmeister S, Jóźwiak K, Schaumann N, Gronewold M, Raap M, Bartels S, Christgen H, Kandt LD, Hillmann P, Lehmann U, Gluz O, Graeser M, Kümmel S, Eulenburg CZ, Harbeck N, Kreipe H, Christgen M. Clinicopathological Characteristics of a Distinct Tumor Phenotype: Invasive Lobular Carcinoma With Tubular Elements in the West German Study Group ADAPTcycle Trial. Lab Invest. 2025 Jun;105(6):104125.
Roberti S, van Leeuwen FE, Hauptmann M, Pfeiffer RM. Building absolute breast cancer risk prediction models for women treated with chest radiation for Hodgkin lymphoma. J R Stat Soc Ser C Appl Stat. 2025 Jan 3;74(2):466-490.
Roberti S, van Leeuwen FE, Diallo I, de Vathaire F, Schaapveld M, Leisenring WM, Howell RM, Armstrong GT, Moskowitz CS, Smith SA, Aleman BMP, Krul IM, Russell NS, Pfeiffer RM, Hauptmann M. Prediction of breast cancer risk for adolescents and young adults with Hodgkin lymphoma. J Natl Cancer Inst. 2025 Apr 1;117(4):619-628.
Roshani S, van Leeuwen FE, Rossetti S, Hauptmann M, Visser O, Zijlstra JM, Hutchings M, Schaapveld M, Aleman BMP. Predicting Absolute Risk of First Relapse in Classical Hodgkin Lymphoma by Incorporating Contemporary Treatment Effects. Cancers (Basel). 2025 Aug 24;17(17):2760
Ruiz-Pérez, G., Ulrich, N., Bettin, J., Lippert, J., Koch, T., von Peter, S (2025) Reduktion und Absetzen von Antipsychotika in der ambulanten Praxis: Perspektiven von Psychiater*innen Nervenarzt (https://doi.org/10.1007/s00115-025-01922-7)
Schwarz, J., Scheunemann, K., Mundry, H., Kula, E., Randzio, N., Salzmann, M., Längle, G., Raschmann, S., Holzke, M., Brieger, P., Hamann, J., Hardt, O., Rout, S., Hirschmeier, C., Herwig, U., Senner, S., Richter, J., Timm, J., Kilian, R., Nikolaidis, K., Weinmann, S., Bechdolf, A., & von Peter, S. (2024). Entwicklung eines vorläufigen Best Practice Modells für stationsäquivalente psychiatrische Behandlung aus Sicht von Nutzer*innen: Konsensprozess mit partizipativen Anteilen [Developing an initial Best Practice Model for inpatient equivalent psychiatric home treatment from the perspective of service users: Consensus process with participatory features]. Psychiatrische PraxisPsychiatr Prax 2025; 52(01): 26-34
2024
de Boo, L.W., Jóźwiak, K., Ter Hoeve, N.D., van Diest, P.J., Opdam, M., Wang, Y., Schmidt, M.K., de Jong, V., Kleiterp, S., Cornelissen, S., Baars, D., Koornstra, R.H.T., Kerver, E.D., van Dalen, T., Bins, A.D., Beeker, A., van den Heiligenberg, S.M., de Jong, P.C., Bakker, S.D., Rietbroek, R.C., Konings, I.R., Blankenburgh, R., Bijlsma, R.M., Imholz, A.L.T., Stathonikos, N., Vreuls, W., Sanders, J., Rosenberg, E.H., Koop, E.A., Varga, Z., van Deurzen, C.H.M., Mooyaart, A.L., Córdoba, A., Groen, E., Bart, J., Willems, S.M., Zolota, V., Wesseling, J., Sapino, A., Chmielik, E., Ryska, A., Broeks, A., Voogd, A.C., van der Wall, E., Siesling, S., Salgado, R., Dackus, G.M.H.E., Hauptmann, M., Kok, M., Linn, S.C. (2024) Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer. ESMO Open. 2024;9(3):102923.
Jóźwiak K, Nguyen VH, Sollfrank L, Linn SC, Hauptmann M. Cox proportional hazards regression in small studies of predictive biomarkers. Sci Rep. 2024 Jun 20;14(1):14232. doi: 10.1038/s41598-024-64573-9. PMID: 38902269; PMCID: PMC11190253.
de Boo LW, Jóźwiak K, Ter Hoeve ND, van Diest PJ, Opdam M, Wang Y, Schmidt MK, de Jong V, Kleiterp S, Cornelissen S, Baars D, Koornstra RHT, Kerver ED, van Dalen T, Bins AD, Beeker A, van den Heiligenberg SM, de Jong PC, Bakker SD, Rietbroek RC, Konings IR, Blankenburgh R, Bijlsma RM, Imholz ALT, Stathonikos N, Vreuls W, Sanders J, Rosenberg EH, Koop EA, Varga Z, van Deurzen CHM, Mooyaart AL, Córdoba A, Groen E, Bart J, Willems SM, Zolota V, Wesseling J, Sapino A, Chmielik E, Ryska A, Broeks A, Voogd AC, van der Wall E, Siesling S, Salgado R, Dackus GMHE, Hauptmann M, Kok M, Linn SC. Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer. ESMO Open. 2024 Mar;9(3):102923
2023
Beeker, T., Witeska-Młynarczyk, A., Meerman, S. T. & Mills, C. (2023). Editorial: Psychiatrization of society. Frontiers in Sociology, 8.
de Vries S, Haaksma ML, Jóźwiak K, Schaapveld M, Hodgson DC, Lugtenburg PJ, Krol ADG, Petersen EJ, van Spronsen DJ, Ahmed S, Hauptmann M, Aleman BMP, van Leeuwen FE. Development and Validation of Risk Prediction Models for Coronary Heart Disease and Heart Failure After Treatment for Hodgkin Lymphoma. J Clin Oncol. 2023 Jan 1;41(1):86-95. doi: 10.1200/JCO.21.02613. Epub 2022 Aug 10. PMID: 35947813.
Harbeck N., Nitz U.A., Christgen M., Kümmel S., Braun M., Schumacher C., Potenberg J., Tio J., Aktas B., Forstbauer H., Grischke E.M., Scheffen I., Malter W., von Schumann R., Just M., Zu Eulenburg C., Biehl C., Kolberg-Liedtke C., Deurloo R., de Haas S., Jóźwiak K., Hauptmann M., Kates R., Graeser M., Wuerstlein R., Kreipe H.H., Gluz O., WSG-ADAPT investigators (2023) De-Escalated Neoadjuvant Trastuzumab-Emtansine With or Without Endocrine Therapy Versus Trastuzumab With Endocrine Therapy in HR+/HER2+ Early Breast Cancer: 5-Year Survival in the WSG-ADAPT-TP Trial. J CLIN ONC, 41 (22): 3796
Kühn L., Lindert L., Kuper P., Prill R., Choi K.E.A. (2023) Research designs and instruments to detect physiotherapy overuse of low-value care services in low back pain management: a scoping review. BMC Health Service Research, 23 (1): 193
Wang Y, Broeks A, Giardiello D, Hauptmann M, Jóźwiak K, Koop EA, Opdam M, Siesling S, Sonke GS, Stathonikos N, Ter Hoeve ND, van der Wall E, van Deurzen CHM, van Diest PJ, Voogd AC, Vreuls W, Linn SC, Dackus GMHE, Schmidt MK. External validation and clinical utility assessment of PREDICT breast cancer prognostic model in young, systemic treatment-naïve women with node-negative breast cancer. Eur J Cancer. 2023 Dec;195:113401.
2022
Beeker, T. (2022). Psychiatrization in mental health care: The emergency department. Frontiers in Sociology, 7. https://doi.org/10.3389/fsoc.2022.793836
Beeker, T. Medikalisierung im psychiatrischen Versorgungsalltag. (2022). Psychologie & Gesellschaftskritik, 2, 37-65.
de Jong, V.M.T., Wang, Y., Ter Hoeve, N.D., Opdam, M., Stathonikos, N., Jóźwiak, K., Hauptmann, M., Cornelissen, S., Vreuls, W., Rosenberg, E.H., Koop, E.A., Varga, Z., van Deurzen, C.H.M., Mooyaart, A.L., Córdoba, A., Groen, E.J., Bart, J., Willems, S.M., Zolota, V., Wesseling, J., Sapino, A., Chmielik, E., Ryska, A., Broeks, A., Voogd, A.C., Loi, S., Michiels, S., Sonke, G.S., van der Wall, E., Siesling, S., van Diest, P.J., Schmidt, M.K., Kok, M., Dackus, G.M.H.E., Salgado, R., Linn, S.C. (2022) Prognostic Value of Stromal Tumor-Infiltrating Lymphocytes in Young, Node-Negative, Triple-Negative Breast Cancer Patients Who Did Not Receive (neo)Adjuvant Systemic Therapy. JOURNAL OF CLINICAL ONCOLOGY. 2022;JCO2101536.
Giardiello D, Hooning MJ, Hauptmann M, Keeman R, Heemskerk-Gerritsen BAM, Becher H, Blomqvist C, Bojesen SE, Bolla MK, Camp NJ, Czene K, Devilee P, Eccles DM, Fasching PA, Figueroa JD, Flyger H, García-Closas M, Haiman CA, Hamann U, Hopper JL, Jakubowska A, Leeuwen FE, Lindblom A, Lubiński J, Margolin S, Martinez ME, Nevanlinna H, Nevelsteen I, Pelders S, Pharoah PDP, Siesling S, Southey MC, van der Hout AH, van Hest LP, Chang-Claude J, Hall P, Easton DF, Steyerberg EW, Schmidt MK. PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients. Breast Cancer Res. 2022 Oct 21;24(1):69.
Gluz O., Nitz U., Kolberg-Liedtke C., Prat A., Christgen M., Kuemmel S., Mohammadian M.P., Gebauer D., Kates R., Paré L., Grischke E.M., Forstbauer H., Braun M., Warm M., Hackmann J., Uleer C., Aktas B., Schumacher C., Wuerstlein R., Graeser M., Pelz E., Jóźwiak K., Zu Eulenburg C., Kreipe H.H., Harbeck N. (2022) De-escalated neoadjuvant chemotherapy in early triple-negative breast cancer (TNBC): Impact of molecular markers and survival analysis of the WSG-ADAPT-TN trial. CLIN CANC RES; 14;28(22):4995-5003.
Hartmann S, Kühn T, Hauptmann M, Stickeler E, Thill M, Lux MP, Fröhlich S, Ruf F, Loibl S, Blohmer JU, Kolberg HC, Thiemann E, Weigel M, Solbach C, Kaltenecker G, Paluchowski P, Schrauder MG, Paepke S, Watermann D, Hahn M, Hufnagel M, Lefarth J, Untch M, Banys-Paluchowski M; Die AXSANA-Studiengruppe. Axillary Staging after Neoadjuvant Chemotherapy for Initially Node-Positive Breast Carcinoma in Germany: Initial Data from the AXSANA study. Geburtshilfe Frauenheilkd. 2022 Sep 13;82(9):932-940.
Kühn L., Lindert L., Choi K.E. (2022) Research designs and instruments to detect physiotherapy overuse of low-value care services in low back pain management: a scoping review protocol. Syst RevV 11 (1): 212
Nitz UA, Gluz O, Kümmel S, Christgen M, Braun M, Aktas B, Lüdtke-Heckenkamp K, Forstbauer H, Grischke EM, Schumacher C, Darsow M, Krauss K, Nuding B, Thill M, Potenberg J, Uleer C, Warm M, Fischer HH, Malter W, Hauptmann M, Kates RE, Gräser M, Würstlein R, Shak S, Baehner F, Kreipe HH, Harbeck N. Endocrine Therapy Response and 21-Gene Expression Assay for Therapy Guidance in HR+/HER2- Early Breast Cancer. J Clin Oncol. 2022 Aug 10;40(23):2557-2567.
Reijers ILM, Menzies AM, van Akkooi ACJ, Versluis JM, van den Heuvel NMJ, Saw RPM, Pennington TE, Kapiteijn E, van der Veldt AAM, Suijkerbuijk KPM, Hospers GAP, Rozeman EA, Klop WMC, van Houdt WJ, Sikorska K, van der Hage JA, Grünhagen DJ, Wouters MW, Witkamp AJ, Zuur CL, Lijnsvelt JM, Torres Acosta A, Grijpink-Ongering LG, Gonzalez M, Jóźwiak K, Bierman C, Shannon KF, Ch'ng S, Colebatch AJ, Spillane AJ, Haanen JBAG, Rawson RV, van de Wiel BA, van de Poll-Franse LV, Scolyer RA, Boekhout AH, Long GV, Blank CU. Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial. Nat Med. 2022 Jun;28(6):1178-1188.
Roberti S, van Leeuwen FE, Ronckers CM, Krul IM, de Vathaire F, Veres C, Diallo I, Janus CPM, Aleman BMP, Russell NS, Hauptmann M. Radiotherapy-Related Dose and Irradiated Volume Effects on Breast Cancer Risk Among Hodgkin Lymphoma Survivors. J Natl Cancer Inst. 2022 Sep 9;114(9):1270-1278.
2021
Beeker, T., Mills, C., Bhugra, D., Te Meerman, S., Thoma, S., Heinze, M., von Peter, S. (2021) Psychiatrization of Society: A Conceptual Framework and Call for Transdisciplinary Research. Front Psychiatry. 2021;12:645556.
Bruch, D., May, S., Prediger, B., Könsgen, N., Alexandrov, A., Mählmann, S., Voß, K., Liersch, S., Loh, J.-C., Christensen, B., Franzen, A., von Peter, S., Pieper, D., Ronckers, C., & Neugebauer, E. (2021). Second opinion programmes in Germany: a mixed-methods study protocol. BMJ Open, 11(2), e045264
Buergy, D., Würschmidt, F., Gkika, E., Hörner-Rieber, J., Knippen, S., Gerum, S., Balermpas, P., Henkenberens, C., Voglhuber, T., Kornhuber, C., Barczyk, S., Röper, B., Rashid, A., Blanck, O., Wittig, A., Herold, H.U., Brunner, T.B., Sweeney, R.A., Kahl, K.H., Ciernik, I.F., Ottinger, A., Izaguirre, V., Putz, F., König, L., Hoffmann, M., Combs, S.E., Guckenberger, M., Boda-Heggemann, J. (2021) Stereotactic body radiotherapy of adrenal metastases-A dose-finding study. Int J Cancer. 2022;151(3):412.
